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MMDB Description
17479Structural Basis for Selectivity of a Small Molecule, S1- Binding, Sub-micromolar Inhibitor of Urokinase Type Plasminogen Activator
14362Crystal Structure of Human Coagulation Factor XA Complexed With Rpr128515
14363Crystal Structure of Human Coagulation Factor XA Complexed With Rpr208815
14364Crystal Structure of Human Coagulation Factor XA Complexed With Rpr208707
49036Coagulation Factor XA Inhibitor Complex
14266Crystal Structure of the Inhibitor Zk-807834 (Ci-1031) Complexed With Factor XA
17720Factor XA Inhibitor Complex
17721Factor XA Inhibitor Complex
3650Structure of Human Des(1-45) Factor XA at 2.2 Angstroms Resolution
24565Human Coagulation Factor XA in Complex With M55532
24566Human Coagulation Factor XA in Complex With M55590
24567Human Coagulation Factor XA in Complex With M55165
24568Human Coagulation Factor XA in Complex With M55159
24569Human Coagulation Factor XA in Complex With M55143
24570Human Coagulation Factor XA in Complex With M55125
24571Human Coagulation Factor XA in Complex With M55124
24572Human Coagulation Factor XA in Complex With M55113
24573Human Coagulation Factor XA in Complex With M54476
24574Human Coagulation Factor XA in Complex With M54471
24575Human Coagulation Factor XA in Complex With M55192
71325Crystal Structure of Human Coagulation Factor XA Complexed With Fxv673
22965Crystal Structure of FXA in Complex With 79
22966Crystal Structure of FXA in Complex With 125
22967Crystal Structure of FXA in Complex With 41
22968Crystal Structure of FXA in Complex With 45
21772Crystal Structure of 3-chloro-n-[4-chloro-2-[[(4- Chlorophenyl)amino]carbonyl]phenyl]-4-[(4-methyl-1- Piperazinyl)methyl]-2-thiophenecarboxamide Complexed With Human Factor XA
21773Crystal Structure of 3-chloro-n-[4-chloro-2-[[(5-chloro-2-pyridinyl) Amino]carbonyl]-6-methoxyphenyl]-4-[[(4,5-dihydro-2-oxazolyl) Methylamino]methyl]-2-thiophenecarboxamide Complexed With Human Factor XA
22115Crystal Structure of Human Coagulation Factor XA Complexed With Rpr132747
22116Crystal Structure of Human Coagulation Factor XA Complexed With Rpr209685
22117Crystal Structure of Human Coagulation Factor XA Complexed With Rpr208944
22118Crystal Structure of Human Coagulation Factor XA Complexed With Rpr200095
24021Crystal Structure of Blood Coagulation Factor XA in Complex With Ecotin M84r
30402Factor XA in Complex With the Inhibitor 1-[6-methyl-4,5,6,7- Tetrahydrothiazolo(5,4-c)pyridin-2-yl] Carbonyl-2- Carbamoyl-4-(6-chloronaphth-2-ylsulphonyl)piperazine
35866Factor XA in Complex With the Inhibitor 4-[(5-chloroindol-2-yl) Sulfonyl]-2-(2-methylpropyl)-1-[[5-(pyridin-4-yl) Pyrimidin-2- Yl]carbonyl]piperazine
52005Factor XA Complexed With a Synthetic Inhibitor Fx-2212a,(2s)-(3'- Amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic Acid
52006Factor XA Complexed With a Synthetic Inhibitor Fx-2212a,(2s)-(3'- Amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic Acid
85261Factor XA in Complex With the Inhibitor 1-(3'-amino-1,2-benzisoxazol- 5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2- Fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (Razaxaban; Dpc906; Bms-561389)
38059Crystal Structure of Factor XA in Complex With 50
38580Crystal Structure of Factor XA in Complex With Compound "1"
34490Factor XA- Cation
38581Crystal Structure of Factor XA in Complex With 21
38582Crystal Structure of Factor XA in Complex With 43
38583Crystal Structure of Factor XA in Complex With Compound 45
39126Crystal Structure of a Human Factor XA Inhibitor Complex
40779Factor XA in Complex With the Inhibitor 2-[[4-[(5- Chloroindol-2-yl)sulfonyl]piperazin-1-yl] Carbonyl]thieno[3,2-b]pyridine N-oxide
63008Factor XA in Complex With the Inhibitor (-)-cis-n1-[(5- Chloroindol-2-yl)carbonyl]-n2-[(5-methyl-4,5,6,7- Tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2- Cyclohexanediamine
63009Factor XA in Complex With the Inhibitor Trans-n1-[(5- Chloroindol-2-yl)carbonyl]-n2-[(5-methyl-4,5,6,7- Tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2- Cyclohexanediamine
63010Factor XA in Complex With the Inhibitor (1s,2r,4s)-n1-[(5- Chloroindol-2-yl)carbonyl]-4-(n,n-dimethylcarbamoyl)-n2- [(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl) Carbonyl]-1,2-cyclohexanediamine
39910Factor XA in Complex With the Inhibitor 1-(3-amino-1,2- Benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl) Methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6- Tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one
41520Factor XA in Complex With the Inhibitor 3-(6-(2'- ((dimethylamino)methyl)-4-biphenylyl)-7-oxo-3- (Trifluoromethyl)-4,5,6,7-tetrahydro-1h-pyrazolo[3,4- C]pyridin-1-yl)benzamide
39360Crystal Structure of the Antithrombin-s195a Factor Xa-pentasaccharide Complex
44472Crystal Structure of Fxaselectidenapc2 Ternary Complex
41858Crystal Structure of a Human Factor XA Inhibitor Complex
41859Crystal Structure of a Human Factor XA Inhibitor Complex
41860Crystal Structure of a Human Factor XA Inhibitor Complex
41863Crystal Structure of a Human Factor XA Inhibitor Complex
45097Crystal Structure of a Human Factor XA Inhibitor Complex
45098Crystal Structure of a Human Factor XA Inhibitor Complex
68915Factor XA - Cation Inhibitor Complex
59214Factor XA in Complex With the Inhibitor Apixaban (Bms- 562247) AKA 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1- Piperidinyl)phenyl)-4,5,6,7-tetrahydro-1h-pyrazolo[3, 4- C]pyridine-3-carboxamide
60521Crystal Structure of the Factor Xanap5 Complex
61950Crystal Structure of Human Factor XA Complexed With 3- Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2- Carboxylic Acid [4-chloro-2-(5-chloro-pyridin-2- Ylcarbamoyl)-6-methoxy-phenyl]-amide
59228Crystal Structure of Human Factor XA Complexed With 3- Chloro-n-(4-chloro-2-{[(5-chloropyridin-2-yl) Amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1h-imidazol- 2-yl)methyl]thiophene-2-carboxamide {pfizer 320663}
54029Factor XA in Complex With the Inhibitor 5-chloro-n-(2-(4-(2- Oxopyridin-1(2h)-yl)benzamido)ethyl)thiophene-2-carboxamide
54030Factor XA in Complex With the Inhibitor 3-chloro-n-((1r,2s)- 2-(4-(2-oxopyridin-1(2h)-yl)benzamido)cyclohexyl)-1h- Indole-6-carboxamide
54031Factor XA in Complex With the Inhibitor 5-chloro-n-((1r,2s)- 2-(4-(2-oxopyridin-1(2h)-yl)benzamido) Cyclopentyl) Thiophene-2-carboxamide
63230An Orally Efficacious Factor XA Inhibitor
54083Factor XA Inhibitor
54127The Discovery of Glycine and Related Amino Acid-based Factor XA Inhibitors
62111X-ray Structure of FXA in Complex With 7-fluoroindazole
45765Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor XA
46798Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor XA
46799Factor XA Inhibitor Complex
68086Structure and Property Based Design of Factor XA Inhibitors: Biaryl Pyrrolidin-2-ones Incorporating Basic Heterocyclic Motifs
68486Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Biaryl P4 Motifs
75079Aminopyrrolidine Factor XA Inhibitor
75080Aminopyrrolidine Factor XA Inhibitor
75081Aminopyrrolidine-related Triazole Factor XA Inhibitor
75082Aminopyrrolidine Factor XA Inhibitor
75083Aminopyrrolidine Factor XA Inhibitor
75084Aminopyrrolidine Factor XA Inhibitor
75085Aminopyrrolidine Factor XA Inhibitor
67853Factor XA in Complex With Bay59-7939
70637Crystal Structure of FXA in Complex With 4,4-disubstituted Pyrrolidine-1,2-dicarboxamide Inhibitor 2
70638Crystal Structure of FXA in Complex With 4,4-disubstituted Pyrrolidine-1,2-dicarboxamide Inhibitor 1
86537Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Monoaryl P4 Motifs
86538Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Monoaryl P4 Motifs
83778Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
83779Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
83780Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
83781Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
83782Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
83783Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
83784Factor XA in Complex With a Pyrrolidine-3,4-dicarboxylic Acid Inhibitor
89156The Discovery of Potent and Long-acting Oral Factor XA Inhibitors With Tetrahydroisoquinoline and Benzazepine P4 Motifs
89157Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Aminoindane and Phenylpyrrolidine P4 Motifs
89158Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Aminoindane and Phenylpyrrolidine P4 Motifs
89159Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Aminoindane and Phenylpyrrolidine P4 Motifs
89160Structure and Property Based Design of Factor XA Inhibitors: Pyrrolidin-2-ones With Aminoindane and Phenylpyrrolidine P4 Motifs
64571Factor XA in Complex With the Inhibitor N-(2-(((5-chloro-2- Pyridinyl) Amino)sulfonyl)phenyl)-4-(2-oxo-1(2h)- Pyridinyl)benzamide
65394Factor XA in Complex With the Inhibitor 1-(4-methoxyphenyl)- 6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3- (Trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin- 7(4h)-one
68815Crystal Structure of Human FXA in Complex With Methyl (2z)- 3-[(3-chloro-1h-indol-7-yl)amino]-2-cyano-3-{[(3s)-2-oxo-1- (2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
78544Factor XA in Complex With the Inhibitor (R)-6-(2'-((3- Hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4, 5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3- (Trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin- 7(4h)-one
78167Crystal Structure of Human FXA in Complex With (S)-2-cyano-1-(2- Methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl) Azepan-3-yl)guanidine
83810Factor XA in Complex With a Cis-1,2-diaminocyclohexane Derivative
78774X-ray Crystal Structure of Human FXA in Complex With (S)-n- ((2-methylbenzofuran-5-ylamino)(2-oxo-1-(2-oxo-2- (Pyrrolidin-1-yl)ethyl)azepan-3- Ylamino)methylene) Nicotinamide
78472Discovery of Tetrahydropyrimidin-2(1h)-one Derivative Tak-44 Potent, Selective and Orally Active Factor XA Inhibitor
80284Factor XA in Complex With the Inhibitor N-(3-fluoro-2'- (Methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- Triazol-3-yl)phenyl)-3-(trifluoromethyl)-1h- Pyrazole-5-car
80285Factor XA in Complex With the Inhibitor 6-(2'- (Methylsulfon Biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3- Phenyl)-3-(trifluoromethyl)-5,6- Dihydro-1h-pyrazolo[3,4-c] 7(4h)-one
80286Factor XA in Complex With the Inhibitor 1-(3-(5-oxo-4,5- DIH 2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- Ylmethyl)biph Yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyri One
80287Factor XA in Complex With the Inhibitor 3-methyl-1-(3-(5- OX Dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'- (Pyrrolidin-1- Biphenyl-4-yl)-5,6-dihydro-1h- Pyrazolo[3,4-c]pyridin-7(4h)
81267Factor XA in Complex With (R)-2-(1-adamantylcarbamoylamino)- 3-(3-carbamidoyl-phenyl)-n-phenethyl-propionic Acid Amide
81592Factor XA in Complex With the Inhibitor 1-[3-(aminomethyl) Phenyl]-n-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3- (Trifluoromethyl)-1h-pyrazole-5-carboxamide (Dpc423)
81593Factor XA in Complex With the Inhibitor 1-[2-(aminomethyl) Phenyl]-n-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3- (Trifluoromethyl)-1h-pyrazole-5-carboxamide (Dpc602)